Antimikrobiální peptidy – terapeutika budoucnosti?

Antimicrobial peptides as future therapeutics? by Václav Čeřovský.

Rapid development of bacterial resistance to the most conventional antibiotics has resulted in an intensive search for alternative antimicrobial agents. Antimicrobial peptides which are part of the innate defense system of practically all living organisms represent promising compounds for developing drugs in the fight against resistant pathogens. Antimicrobial peptides kill bacteria by the disruption of their membrane which is substantially different mechanism from that of conventional antibiotics. We describe remarkable group of cationic helical antimicrobial peptides identified in the venom of hymenopteran insects.